Nayyar Iqbal Selected Research

saxagliptin

1/2022	Long-term effects of dapagliflozin plus saxagliptin versus glimepiride on a background of metformin in patients with type 2 diabetes: Results of a 104-week extension to a 52-week randomized, phase 3 study and liver fat MRI substudy.
1/2019	Sustained 52-week efficacy and safety of triple therapy with dapagliflozin plus saxagliptin versus dual therapy with sitagliptin added to metformin in patients with uncontrolled type 2 diabetes.
8/2018	Characterization of the Open-Label Lead-In Period of Two Randomized Controlled Phase 3 Trials Evaluating Dapagliflozin, Saxagliptin, and Metformin in Type 2 Diabetes.
1/2018	Safety and tolerability of dapagliflozin, saxagliptin and metformin in combination: Post-hoc analysis of concomitant add-on versus sequential add-on to metformin and of triple versus dual therapy with metformin.
1/2017	Nonclinical and clinical pharmacology evidence for cardiovascular safety of saxagliptin.
1/2017	Effect of Saxagliptin on Renal Outcomes in the SAVOR-TIMI 53 Trial.
9/2016	Saxagliptin Efficacy and Safety in Patients With Type 2 Diabetes and Moderate Renal Impairment.
8/2016	Predisposing Factors for Any and Major Hypoglycemia With Saxagliptin Versus Placebo and Overall: Analysis From the SAVOR-TIMI 53 Trial.
11/2015	Randomized, Double-Blind, Phase 3 Trial of Triple Therapy With Dapagliflozin Add-on to Saxagliptin Plus Metformin in Type 2 Diabetes.
11/2015	Randomized, Double-Blind Trial of Triple Therapy With Saxagliptin Add-on to Dapagliflozin Plus Metformin in Patients With Type 2 Diabetes.

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Nayyar Iqbal Research Topics

Disease

50	Type 2 Diabetes Mellitus (MODY) 01/2022 - 08/2004
17	Body Weight (Weight, Body) 01/2021 - 04/2009
17	Insulin Resistance 10/2016 - 05/2003
13	Weight Loss (Weight Reduction) 01/2018 - 05/2003
10	Cardiovascular Diseases (Cardiovascular Disease) 01/2020 - 08/2004
9	Hypoglycemia (Reactive Hypoglycemia) 08/2018 - 01/2009
8	Atherosclerosis 01/2013 - 05/2003
7	Infections 10/2021 - 02/2013
7	Coronary Artery Disease (Coronary Atherosclerosis) 10/2021 - 08/2004
7	Myocardial Infarction 01/2020 - 02/2014
6	Diabetic Ketoacidosis (Ketoacidosis, Diabetic) 01/2021 - 03/2015
6	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2021 - 03/2015
6	Stroke (Strokes) 01/2020 - 02/2014
6	Diabetes Mellitus 12/2019 - 02/2009
6	Pancreatitis 08/2019 - 09/2005
6	Metabolic Syndrome (Dysmetabolic Syndrome X) 07/2011 - 05/2003
5	Heart Failure 11/2019 - 09/2008
5	Urinary Tract Infections (Urinary Tract Infection) 01/2018 - 02/2013
5	Inflammation (Inflammations) 10/2010 - 09/2004
4	Hyperglycemia 11/2016 - 01/2007
4	Obesity 01/2007 - 11/2004
4	Morbid Obesity 07/2005 - 05/2003
3	Peripheral Arterial Disease 10/2021 - 02/2010
3	Hypertension (High Blood Pressure) 03/2016 - 01/2007
2	Gangrene 10/2021 - 01/2012
2	Albuminuria 10/2020 - 01/2017
2	Neoplasms (Cancer) 01/2019 - 10/2014
2	Pancreatic Neoplasms (Pancreatic Cancer) 01/2018 - 09/2014
2	Renal Insufficiency (Renal Failure) 08/2016 - 04/2012
2	Dengue (Dengue Fever) 01/2016 - 04/2012
2	Thrombocytopenia (Thrombopenia) 01/2016 - 10/2014
2	Scrub Typhus (Typhus, Scrub) 01/2016 - 01/2013
2	Headache (Headaches) 01/2015 - 10/2013
2	Pain (Aches) 10/2013 - 04/2012
2	Overweight 05/2010 - 06/2006
2	Thrombosis (Thrombus) 01/2007 - 08/2004
1	Foot Ulcer 10/2021
1	Breast Neoplasms (Breast Cancer) 08/2020
1	Thyroid Neoplasms (Thyroid Cancer) 01/2019
1	medullary Thyroid cancer 01/2018
1	Unstable Angina 01/2018
1	Injection Site Reaction 01/2017
1	Diabetic Nephropathies (Diabetic Nephropathy) 01/2017
1	Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left) 10/2016

Drug/Important Bio-Agent (IBA)

21	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 04/2009
20	dapagliflozinIBA 01/2022 - 02/2013
18	saxagliptin FDA Link 01/2022 - 10/2013
16	Insulin (Novolin)FDA Link 10/2021 - 11/2004
15	Metformin (Glucophage)FDA LinkGeneric 01/2022 - 11/2010
15	Exenatide (Byetta)FDA Link 10/2020 - 04/2016
7	LipidsIBA 04/2016 - 05/2004
6	CarbohydratesIBA 10/2010 - 05/2003
5	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 10/2020 - 03/2014
5	AdipokinesIBA 01/2013 - 01/2005
4	SuspensionsIBA 10/2020 - 01/2017
4	omega-Chloroacetophenone (Mace)IBA 01/2020 - 02/2014
4	Glucagon-Like Peptide-1 ReceptorIBA 12/2019 - 04/2016
4	Sodium-Glucose Transport ProteinsIBA 11/2016 - 01/2014
4	Immunoglobulin M (IgM)IBA 01/2016 - 04/2012
4	C-Reactive ProteinIBA 01/2011 - 08/2004
3	Sodium-Glucose Transporter 2 InhibitorsIBA 01/2021 - 03/2015
3	Glucagon-Like Peptide-1 Receptor AgonistsIBA 08/2019 - 01/2017
3	HDL CholesterolIBA 01/2019 - 03/2006
3	Hemoglobins (Hemoglobin)IBA 10/2018 - 07/2011
3	Triglycerides (Triacylglycerol)IBA 02/2011 - 05/2003
3	Lipoproteins (Lipoprotein)IBA 02/2011 - 09/2004
3	CalciumIBA 02/2011 - 04/2007
3	AdiponectinIBA 10/2010 - 01/2005
3	LeptinIBA 10/2010 - 08/2004
2	SodiumIBA 01/2021 - 03/2017
2	IncretinsIBA 08/2019 - 01/2017
2	CholesterolIBA 01/2019 - 04/2009
2	Sitagliptin Phosphate (Januvia)FDA Link 01/2019 - 01/2017
2	LDL CholesterolIBA 01/2019 - 08/2009
2	Hypoglycemic Agents (Hypoglycemics)IBA 08/2016 - 01/2014
2	AntibodiesIBA 01/2016 - 01/2015
2	Proteins (Proteins, Gene)FDA Link 01/2015 - 11/2004
2	Glucagon (Glukagon)FDA Link 11/2014 - 08/2014
2	Apolipoproteins B (ApoB)IBA 02/2011 - 08/2009
2	Biomarkers (Surrogate Marker)IBA 10/2010 - 02/2010
2	CytokinesIBA 01/2005 - 11/2004
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2005 - 11/2004
1	glimepiride (Amarel)FDA LinkGeneric 01/2022
1	Hormones (Hormone)IBA 08/2020
1	Biological ProductsIBA 08/2020
1	boldenone undecylenate (Equipoise)IBA 01/2020
1	Glucagon-Like Peptide 1 (GLP 1)IBA 12/2019
1	Tumor Biomarkers (Tumor Markers)IBA 01/2019
1	Calcitonin (Calcitonin, Eel)FDA LinkGeneric 01/2019
1	Dipeptidyl-Peptidase IV InhibitorsIBA 01/2017
1	Glyburide (Glibenclamide)FDA LinkGeneric 08/2016
1	Short-Acting InsulinIBA 08/2016

Therapy/Procedure

24	Therapeutics 01/2021 - 03/2006
16	Glycemic Control 10/2020 - 05/2004
6	Carbohydrate-Restricted Diet (Low Carbohydrate Diet) 06/2006 - 05/2003
3	Fat-Restricted Diet (Diet, Fat Restricted) 10/2010 - 05/2003
2	Surgical Amputation (Amputations) 10/2021 - 12/2019
2	Drug Therapy (Chemotherapy) 08/2020 - 01/2018
1	Adjuvant Chemotherapy 08/2020
1	Subcutaneous Injections 01/2017